1. E-Pharmacy regulations in India: Past, present, and future
The advent of digitalization has taken India by storm and the pharma sector is also not left behind. The trend of purchasing medicine online is increasing and so is the number of e-pharmacy start-ups. E- Pharmacies are recent entrants in the Indian e-commerce industry and receiving attention from the government as well as global investors from the past three years. The Ministry of Health and Family Welfare, Government of India has published draft rules on 28th August 2018, with the heading “Sale of drugs by e-pharmacy” to bring e-pharmacies within the scope of Drug and Cosmetics Rules, 1945 by making amendments in it which currently does not distinguish between online and brick and mortar pharmacies. It aims to regulate online sale of quality medicines pan India through e-pharmacies registered under Central Drugs Standard Control Organisation (CDSCO), India’s apex drug regulator and central licensing authority, where all records are maintained as per rules laid down. The confidentiality of patient details have to be maintained and cannot be disclosed to anyone one under any circumstances other than the central or state government as the case may be. The sale of tranquilizers, narcotic and psychotropic substances and Schedule X drugs are not permitted through e- pharmacies. The dawn of 2019 is expected to bring a brighter future for a fully legitimate and professionally managed E- Pharmacies in India.
Published by: Priya Nair S., Dr. Anil Middha
Research Area: Pharmacy Regulation
2. Medical management of Dysmenorrhea
Dysmenorrhea is a very common problem affecting women and may be primary or secondary. Pain in dysmenorrhea is mediated by hypersecretion of prostaglandins and uterine hypercontractility. Secondary dysmenorrhea is due to some underlying pathology like endometriosis, adenomyosis. The treatment options include NSAIDS as first line drugs, Oral contraceptives alone or in combination with NSAIDS or progestins. Cases refractory to combined therapy need further evaluation to rule out a secondary cause.
Published by: Rajni Mittal
Research Area: Obstetrics & Gynaecology
3. Role of contemporary therapy in treatment of dysmenorrhea
Dysmenorrhea affects women during reproductive years and is a cause of frequent absenteeism. Conventionally dysmenorrhea has been treated by NSAIDS and oral contraceptives. They have a failure rate of >15% and are limited by side effects and may be contraindicated in others. People have used contemporary therapies for several years to relieve pain during menses and associated symptoms. These therapies include herbal therapy, heat, yoga, and physiotherapy. Each one of them is effective in relieving pain during menses and effects are almost comparable to NSAIDS and have fewer side effects. Further research is required to recommend them as first-line treatment in dysmenorrhea.
Published by: Rajni Mittal
Research Area: Obstetrics And Gynaecology
4. Fistulotomy or LIFT: Which has better outcome in management of intersphincteric and low transphincteric fistula-in-ano– A randomized prospective study
Anal Fistula in ano is an abnormal connection between ano-rectum and the perianal skin. It is a common condition with a prevalence of 12 to 28/100,000 of population per year. There are many techniques to manage this condition. The aim of each surgery is to prevent recurrence and anal incontinence with early healing with decreased post-operative morbidity. LIFT and Fistulotomy are common types of surgery used in the management of Fistula in ano. This aim of this study is to compare the outcomes of the two procedures LIFT and Fistulotomy in cases of Intersphincteric and Low Trans-sphincteric fistulas primarily in term of healing, infection, recurrence, and anal incontinence. This prospective study was carried out in the Department of Surgery at North Delhi Municipal Corporation Medical College and Hindu Rao Hospital, Delhi between April 2017 and November 2017. A total of 50 cases were taken up and assigned either procedure randomly. Patients with recurrent fistulas, complex fistulas, high fistulas, fistulas with more than one external openings and fistulas due to secondary causes (Koch’s, Crohn’s Malignancy, post-radiation) and those with systemic diseases such as diabetes, HIV, immunosuppressive conditions were excluded. The patients were followed up for maximum 12 months studying recurrence, incontinence and post-operative morbidity. Of 50 patients 45 were males and 5 females all presenting with a history of recurrent perianal discharge. All patients underwent clinical examination, digital fistulogram, trans anal USG (12 patients) and/or MR Fistulogram to assess the characteristics of the fistula. 22 patients underwent LIFT and 28 underwent Fistulotomy. 25 patients were followed up for 3 months and rest for 2 months. There was recurrence in 4 patients (3 in LIFTand one in fistulotomy), unhealed sinus in 10 patients (7 in LIFT and 3 in fistulotomy) which required re-surgery. No patients had incontinence and 15 patients (10 –LIFT and 5- Fistulotomy) had delayed healing (4 to 6 wks).
Published by: Dr. Rajiv Nandan Sahai
Research Area: General Surgery
5. Post-operative fever
Post-operative fever is common and occurs in about 30% of patients. Non-Infectious causes are more common and occur usually in the first 24 hours while infectious causes can occur anytime. The presentation of infectious and non-infectious cause is almost the same and it is important to know the cause of fever so as to investigate and treat the patient in minimum cost yet in an effective manner.
Published by: Dr. Rajni Mittal, Dr. Rajiv Nandan Sahai
Research Area: General Surgery
6. Comparative study of different codes on steel building
The paper mainly focuses on the comparison of two different code that is IS code is IS800: 2007 (LSM), IS 875: 1987 part (I, II, and III) and AISC LRFD code for a conventional industrial steel building. It’s a case study for the industrial building based on the review and the various case studies which show their experimental and analytical study carried out in this field. Different structural design code provides different data and procedure of design to engineering. Comparisons of the different factor with the same loading. To conduct the study a 3D model of Industrial building having dimension 15mX45m, 20mX50m, 23mX65mwith three different spacing that is (4.5m,5m,6m); (5m,6m,7m); (5m,6m,7m) having column height 6m is designed and analyzed on STADD-Pro V8i structural design software.
Published by: Siddhitee N. Sabnis, Mohd. Shahezad
Research Area: Structural Engineering
7. Biomarkers- Emerging applications of biomarkers in healthcare
Biomarkers are a small protein or peptide molecules which are part of cell receptors, cell signaling molecules involved in cell-cell signaling or cell protein kinase activation and transfer of the signal to the nucleus with the regulation of gene transcription. Biomarkers have functional significance in the recognition of different stages of cancer, therapy for cancer, and the identification of different types of cancer of different organs according to the biomarker present. It is also used for the diagnosis and analysis of mutations in various proteins and identification of single nucleotide polymorphism in genes, screening of diseases, classification of diseases in humans and development of target inhibitor molecules against the biomarkers. Various other studies have indicated the presence of autoantibodies against proteins of the cells which act as biomarkers in different grades of cancer and autoimmune response.
Published by: Dr. Sulabh Kharbanda
Research Area: Oncology
8. Impact of Prime Minister Ujjwala Yojana on ocular trauma in the tribal belt of India
We wanted to study the impact of Ujjwala yojana on ocular injuries caused by the use of wooden sticks during cooking. This is a retrospective cohort study. We retrieved the data from the electronic medical record (EMR) of ocular injuries caused by the use of wooden sticks during cooking before and after launching of Pradhanmantri Ujjwala yojana, a government of India flagship program, in which free LPG connections are given to below poverty line (BPL) families. We collected the data regarding ocular injuries caused by the use of wooden sticks during cooking. During our study, period 8,17,336 new LPG connections were provided under this scheme in the study population. We enrolled 3261 ocular injury cases; of which, 171 (5.3%) eyes were found to have ocular injuries because of using wooden sticks during cooking. We divided ocular injury cases that are caused by the use of wooden sticks during cooking into two groups: before and after launching of the Ujjwala yojana. We found that the number of eyes injured before and after the launch of the scheme are 93 (54%) and 78 (45%), respectively. The difference between the two groups was statistically significant (p=0.000). Ujjwala Yojana is beneficial in reducing ocular injuries caused by the use of wooden sticks during cooking.
Published by: Dr. Shreya Shah, Dr. Mehul Shah
Research Area: Ocular Trauma
9. Performance analysis of EPMS and EAPMS routing protocol in WSN
Routing in a wireless sensor network is a key challenge. The appropriate routing is done in WSN by using swarm intelligence approach. Various swarm intelligence techniques are available like ant colony optimization, particle swarm optimization, artificial bee colony optimization etc. But the hybrid approach of ACO and PSO is a promising one. the PSO is used to enhance the attributes in the ACO, which define that the selection of parameter doesn’t depend on artificial experience, but relies on the robust search on the particles in the PSO. We also used an enhance utilization of ACO, by this technique we have found the shortest path or routes of ants. The output of the experiment shows that the optimize algorithm not only reduce the number of paths in the ACO but also finding the shortest path at the place of the largest path. The simulation result shows that the combination of ACO-PSO performs better than Energy Efficient PSO in terms of dead nodes, alive nodes, and throughput of the network.
Published by: Kiran Gandhi, Varsha
Research Area: Wireless Sensor Network
10. Fabrication of Jute–Pine Apple leaf reinforced hybrid composites: Validation of mechanical properties through ANSYS
There is a huge need for new materials in all fields of engineering, this invites the development of new ¬materials which suits the need. Utilization of biodegradable materials i.e. natural fibers for various applications to preserve the environment from synthetic fibres invites the development of natural fiber reinforced polyester composites. In a country like India which is producing an enormous amount of agricultural solid waste (in the form of leaf, fruits, stems etc.) there is lack of marketing for the above-said wastes if this can be improved the farmers may get benefited. Natural fiber reinforced composites are preferred than conventional materials because of their advantages like low density, lightweight, high strength to weight ratio, low cost, high toughness, and biodegradability. The present investigation deals with the preparation of jute, pineapple leaf fiber and jute-pineapple leaf fiber (Hybrid) reinforced polyester composite and to determine the tensile, flexural and impact properties with increase in percentage weight fraction of the fiber and to compare the properties of the composites. Further, the experimental results will be validated through ANSYS software.
Published by: Tanniru Dinesh, Dr. S. Madhusudan
Research Area: Mechanical Engineering
11. Formulation of a class of solvable standard cubic congruence of even composite modulus
In this paper, a class of solvable standard cubic congruence of composite modulus is formulated. A formula for solutions is established and found true by solving some examples. It is also found that the congruence has exactly three solutions. Establishment of the formula for the solutions is the merit of the paper. It is needless to use Chinese Remainder Theorem. The formulation is the alternative of CRT which gives solutions directly in a short time.
Published by: B. M. Roy
Research Area: Mathematics
12. Fuzzy Z-precontinuous functions in fuzzy topological space
In this paper, we introduce the classical form of Z-continuous functions under the fuzzy setting in the name of “Fuzzy Z-Precontinuous functions in Fuzzy Topological Spaces”. A weaker form of fuzzy Z-continuous function, called fuzzy Z-precontinuous function is introduced and its properties and characterizations are discussed.
Published by: M. Regina, G. Saravanapriya, N. Girija, Dr. V. Margret Ponrani
Research Area: Mathematics
13. Development of sandwich panels combining aluminium powder-cement composites lightweight concrete
The heavy dead weights of concrete structures are posing a headache for the structural engineers to design the various members much complicated to take its own weight. The present investigations are carried out to develop a simple, lightweight and cost-effective technology for replacing the existing wall systems. In this paper, we have used the materials Portland pozzolana cement (PPC) is matrix materials and the reinforcing materials is aluminum powder, bamboo natural fiber. The methodology of this paper is a sand casting process used to produces the composite plate or bars. The composition of reinforced samples is Lightweight Concrete (LC) mixes were prepared with 0%, 0.25%, 0.5%, 0.75%, 1%, 1.25%, 1.5%, 1.75%, 2%, of foaming agent by weight of cement In this paper we are tested in deflection behavior, tensile test and compressive test.
Published by: R. Balasubramanian
Research Area: Composites Materials
14. Assessing of Place- making aspects in beach precinct: Case of Vishakhapatnam
Placemaking is process of creating “people-oriented” places by enriching urban life experiences in public places. One of the aspects of place making is to provide place identity, which is mainly determined by the “sense of place” experienced by users. The study is aimed at investigating place- making approach in an urban public space. It does so by exploring connections between the human experience, aspirations and the physical dimension of space by onsite phenomenological research of criteria for successful places established by Project for Public Places and urban design qualities for improved liveability. A primary case study concentrating on R.K beach precinct in Vishakhapatnam has been demonstrated to analyse the ways in which people use, value and relate to this public beach. The analysis of study revealed factors that contribute to everyday experiences of spaces of built and unbuilt environment as key components of experience of quality in public realm.
Published by: Sansriti Vardhan
Research Area: Urban Design And Development
15. Performance of green banking and its effects on economy in Bangladesh
Green banking has become a buzzword in the banking arena in Bangladesh and all over the world in recent times. Green banking is defined as an 'eco-friendly socially responsible banking' which not only plays the role of financing intermediary but also works on achieving objectives towards a healthy environment for the present generation and future generation as well. We live in a competitive world where everything is relative. Everybody wants to be better than others and one’s activities sometimes cause environmental change and damage. So to save environment Green banking is a part of a green initiative taken by banks. Environmentally friendly policies can be applied so that green bank can grow in every sector of its activities without changing its main banking functions. It can also augment the goodwill of the institute and promote a 'green and social consciousness image' in the society. Although this theme has been implemented in several developed countries promoting the slogan 'Be green, Go green', it is a very useful starting point for developing countries like Bangladesh to follow. This paper observes the existing practices of green banking in Bangladesh and has made an endeavor to highlight systems, opportunities, difficulties, and advantages of green banking policies. In this study, secondary data from Bangladesh Bank Reports and other commercial bank reports have been used. These Results show that the 'Bangladesh Bank', formulated policies, strategies and allocated budgets to commercial banks with respect to green initiatives. Special packages for green projects can eliminate the present problems and can help to face the challenges and consequently accelerate green banking activities.
Published by: Tahsin Sharmila Raisa, Amima Najnin Maria
Research Area: Economics
16. Systematic literature review for secure exchange of EHR within inter health organisation using cloud computing for India
Our purpose of the study is to implantation of EHR and current challenges of secure exchange of EHR within inter Health Organisation. EHR is created by many hospitals for ease of doctor and patient the main objective to create EHR is to develop a paperless system. EHR is used by only Healthcare organization or hospitals where it is created but patient electronic record required by another Healthcare organization again it will create a problem for exchanging record within inter Health Organisation the main objective of a literature review is to present a systematic way for secure exchange of EHR within inter Healthcare organization using the cloud.
Published by: Shraddha Dudhani, Manish Dudhani
Research Area: Security And Cloud Computing In Healthcare.
17. An evaluation of women empowerment through microfinance: Factor analysis
Financial inclusion of the Government through banking institutions particularly to empower rural/tribal women in India is endowed to focus upon such households which are left out in terms of employment avenues. However, rural/tribal unemployed women who have entrepreneurial capabilities, but are unable to pursue starting a business due to the shortage of financial sources, can avail financial support and succeed in the process of socio-economic development by generating employment avenues for their families. Keeping motive of microfinance for SHGs in mind, an attempt has been made to analyze to what extent; microfinance has proved instrumental in empowering tribal women of Himachal Pradesh.
Published by: Dr. Deepika Gautam, Dr. Alok Kumar
Research Area: Finance
18. Data security in cloud computing
Cloud computing is a globalized concept and there are no borders within the cloud. Computers used to process and store user data can be located anywhere on the globe, depending on where the capacities that are required are available in the global computer networks used for cloud computing. Because of the attractive features of cloud computing, many organizations are using cloud storage for storing their critical information. The data can be stored remotely in the cloud by the users and can be accessed using thin clients as and when required. One of the major issue in the cloud today is data security in cloud computing. Storage of data in the cloud can be risky because of use of the Internet by cloud-based services which means less control over the stored data. One of the major concern in the cloud is how do we grab all the been ts of the cloud while maintaining security controls over the organizations' assets. Our aim is to propose a more reliable, decentralized lightweight key management technique for cloud systems which provides more e client data security and key management in cloud systems. Our proposed technique provides better security against Byzantine failure, server colluding and data modi cation attacks. Keywords: Cloud security; key management; server colluding attacks; Byzantine failure;
Published by: Kumar Kishan Chandra, Supriya Raj, Dr. Anand Kumar Pandey
Research Area: Cloud Computing
19. Smarandache hyper (∩, ϵ)-filter on Smarandache hyper K-algebra
We introduce the notion of a Smarandache hyper (∩, ϵ)-filter and ω-reflexive in hyper K-algebra and some properties related to it.
Published by: Ameena Beave D., Fathima Bazeela S.
Research Area: Algebra
20. Assessment of noise pollution in Raipur city of Chhattisgarh, India
In developing countries like India Assessment of Noise pollution is an important task. Noise pollution adversely affects the health of human beings. The most important noises sources of noise are road traffic, aircraft, railways and industries, noise in the community from industrial and construction site and noise at home. Road traffic is by far the largest of these, and accounts for about 78 per cent of noise annoyance. In India, vehicular traffic is increasing rapidly, which has given birth to overcrowded roads and noise pollution. This study is primarily focusing on the monitoring of noise pollution at different places of Raipur City. In this study, noise monitoring was carried out with the help of sound level meter model (VA8080). Some important places of Raipur have been selected for noise level study purpose. All the places are categorized under different zones i.e. commercial zone, silent zone, industrial zone, and residential zone. All data were collected between 07:00 am to 09:00 p.m. Every hour the noise levels have been measured. To make the noise level more accurate each reading were taken in a gap of 6 minutes, that is, 10 readings per hour. And the average of the readings was taken as per hour sound intensity level. The study period of the survey was 15 days. Therefore this study reveals that the noise levels are higher than the standard level foe each zones.
Published by: Vishal Kumar, Vaishali Pendse
Research Area: Environment Engineering
21. Preparation of polyurethane coating based on polyesteramide polyol of castor oil of fatty acid and isocyanate
Polyurethane networks based on polyesteramide polyol using castor oil and diethanolamide (DEA) were proposed to study doing this wide. To utilize oil in the preparation of polyesteramide polyol (PEA). The chemical structure of the synthesized resin was characterized by spectroscopic techniques like FTIR, NMR etc. Various physical properties such as acid value, saponification value, iodine value, hydroxyl value, the amine value of resin were also determined. CO was then converted into diethanolamide castor oil of mixed fatty acid using 0.5 % sodium methoxide as a catalyst and converted to polyesteramide resin after with various dibasic acid in presence of xylene as azeotropic solvent. PU themselves were prepared from the reaction of polyester amide polyol of castor oil (PEA) and isocyanate-terminated polyurethane prepolymer. The PU coating obtained was then analyzed for its physical-chemical, film performance properties and resistance to the various chemical.
Published by: Swapail Shrirame, Pradeep G. Shende
Research Area: Polymeric Coating
22. Comparative study of therapeutic efficacy of conservative management and ultrasound guided pigtail drainage of amoebic liver abscess
Liver abscess is a common condition in India which is associated with high morbidity and mortality. ALA is the most common extra intestinal site of infection but occurs in only less than 1% of E. histolytica infections. The mortality rate has been estimated to be around 0.2-2.0% in adults and up to 26% in children. There are many options in managing amoebic liver abscess such as medical management, percutaneous or open surgical drainage. Until now there have been no studies which have compared the therapeutic efficacy between pigtail drainage and conservative management in medium-sized (5 to 10 cm). Nor is there any prospective study aimed at identifying parameters for instituting medical management versus drainage procedure for abscesses measuring between 5.0 and 10.0 cm. The aim of this paper is to compare the efficacy of conservative medical management to ultrasound-guided pigtail drainage and establish objective criteria for the management of such abscesses. This is a prospective study of 100 cases of amoebic liver abscess (ALA) of medium size (5 to 10 cm) presenting to the Surgical Emergency and Surgical Outpatient Department of Hindu Rao Hospital from the period January 2014 to March 2015. All patients included were diagnosed as having an amoebic liver abscess (ALA) based on a history of anorexia, malaise, fever and pain abdomen with or without a preceding history of diarrhea and findings of tender hepatomegaly, intercostal tenderness, leucocytosis amoebic serology (ELISA) and ultrasound evidence of amoebic liver abscess. Patients were randomly allocated into two groups by double-blinded secret envelop method. Group, I patients consisted of 25 patients who were treated with antiamoebic (metronidazole 750 mg tid / IV 500mg 6 hourly) and antibiotic (ciprofloxacin 500 mg bd) drugs. Group II patients also consisted of 25 patients who were treated by ultrasound-guided indwelling pigtail catheter drainage in addition to antiamoebic (metronidazole) and antibiotic (ciprofloxacin) drugs. Improvement in pain, fever, anorexia and clinical signs of hepatomegaly, pulse rate, respiratory rate, and USG abdomen within 72 hours of an institution of therapy was considered as criteria for continuing that particular modality of treatment. At three to five days, patients’ outcome was assessed and if they did not respond to the first modality of treatment, the patient was subjected to the second modality of treatment, i.e. conservative converted to pigtail insertion and patients with pigtail insertion for drainage. A comparison was made between clinical signs and investigations to assess the patients It was found all patients of Study Group II (pigtail drainage) had earlier improvement of all parameters of response to than patients in Study Group I (conservative management) and this response was significant. Another significant finding of this study was abscesses of size > 10 cm should be aspirated or drained. This study showed that the abscesses of size between 6.0 cm to 10.0 cm should be taken up for pigtail catheter drainage at presentation as the time of resolution and improvement in clinical and investigative parameters were more rapid in Group II as compared to Study Group I with almost no complications associated with pigtail insertion. For abscesses >10 cm and in those ALA associated with complications insertion of pigtail was beneficial. Abscesses less than 6.0 cm could be managed with medical treatment alone.
Published by: Dr. Rajiv Nandan Sahai, Dr. Raju Patel
Research Area: General Surgery
23. 3- DPGR (3-Level Daubechies wavelet, PCA, GLCM, and RBF Kernal) method used for brain MRI categorization
Today image processing assumes a critical part in the restorative field and medicinal imaging is a developing and testing field. Therapeutic imaging is invaluable in the determination of the illness. Numerous individuals experience the ill effects of cerebrum tumor, it is a genuine and perilous infection. Restorative imaging gives a legitimate finding of cerebrum tumor. There are numerous procedures to identify mind tumor from MRI pictures. These techniques confront challenges like finding the area and size of the tumor. To identify the tumor from the mind is the most critical and troublesome part, picture division is utilized for this. Effectively, different calculations are produced for picture division. This audit paper covers the essential wordings of mind tumor, a survey of different cerebrum tumor division procedures.
Published by: Bharti, Bharti, Manit Kapoor
Research Area: Brain Tumor