In Vitro Antioxidant Potential of Pure Fractions of Eclipta Alba
Abstract–Oxidative stress and Ultraviolet (UV) irradiation-induced skin damage, is involved in numerous diseases. Eclipta alba which belongs to Asteraceae family is used traditionally in ayurvedic system of medicine in India for the treatment of liver diseases. Our study shows that water extract of E. alba has a potent effect in scavenging 1, 1-diphenyl-2-picrylhydrazyl (DPPH), chelating ferrous ion, and superoxide radicals, exhibiting IC50 values of 0.21 mg/mL, 1.20 mg/mL, and .49 mg/mL, respectively. Identification and quantification of the wedelolactone, one of the active constituents of the Eclipta alba plant extract, was carried out by HPLC analysis. The result of the present study indicates that the Eclipta alba extract shows a high amount of ascorbic acid, tannins, flavonoids, phenolics, contents. The hydroalcoholic extract of Eclipta alba effectively scavenged free radicals at all different concentrations and showed potent antioxidant potency. Eclipta alba extract shows antioxidative properties.
Published by: Anjali Singh, Ayodhya Singh, Vandana Dwivedi
Author: Anjali Singh
Paper ID: V3I1-1366
Paper Status: published
Published: February 20, 2017
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