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A prospective study to assess the clinical risk factors and the drug utilization pattern in female patients with gestational hypertension

Hypertension in pregnancy is a pregnancy-specific, multisystem disorder characterized by the development of edema, elevated blood pressure and proteinuria after 20 weeks of gestation. The hypertensive disease occurs in 5% to 10% of all pregnancies and is a major cause of maternal and perinatal morbidity and mortality. A prospective observational study was performed to assess the risk factors that potentiate gestational hypertension and also to evaluate the drug utilization pattern in patients diagnosed with gestational hypertension. 72 patients who were admitted with gestational hypertension in the Gynaecology department of Pushpagiri Medical College Hospital were enrolled for this study. A standardized data collection form was prepared and necessary data were collected which includes the demographic details, obstetric history, past medical history, past medication history, current medication etc. The risk factors, complications associated with gestational hypertension and drug utilization pattern were analyzed. Pre-existing hypertension and diabetes mellitus are found to be the most common risk factors of gestational hypertension in this study. Most commonly prescribed anti-hypertensive drug was Labetalol and found to be safe. The antihypertensive drug therapy was found to be significant. From the study, it was found out that the overall drug utilization pattern in gestational hypertension patients was in accordance with the specific hypertensive treatment guidelines.

Published by: Mathew George, Lincy Joseph, Naveena Susan Symon

Author: Mathew George

Paper ID: V4I4-1466

Paper Status: published

Published: August 14, 2018

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Research Paper

A method to discover constant conditional functional dependencies for a given relation

This CCFD paper explores the idea of discovering the constant conditional functional dependencies (CCFDs). Constant CFDs are particularly important for object identification, which is essential to data cleaning and data integration. The further algorithm provides a set of cleaning rule discovery tools for users to choose it for different applications. These CCFDs are derived from conditional functional dependencies (CFDs). The algorithm is implemented for finding the constant conditional functional dependencies from a given relation.

Published by: Sneha Sadalagi, Dr. P V Kumar

Author: Sneha Sadalagi

Paper ID: V4I4-1460

Paper Status: published

Published: August 14, 2018

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Research Paper

Choice of antibiotics/antiviral agents in patients with sepsis of different aetiologies

Sepsis is a potentially life threatening complication of an infection. Sepsis occurs chemical released into bloodstream to fight the infection trigger inflammatory response through the body. This inflammation can trigger a cascade of changes that can damage multiple organ system, causing them to fail. Septic shock is defined as sepsis associated with hypotension and perfusion abnormalities despite the provision of adequate fluid resuscitation. Patients with septic shock who are receiving inotropic or vasopressor therapy might still exhibit perfusion abnormalities, despite the lack of hypotension. This was a prospective observational study, which included 75 patients admitted in Pushpagiri Medical College Hospital. The study was done to evaluate the choice of drug in patients with sepsis along with the type of organism and time of treatment, and additional therapy given to the patient. From the present study, it was suggested that the use of antibiotic therapy, especially a broad spectrum antibiotic was the most appropriate initial therapy. Majority of the population uses the broad spectrum antibiotic (Piperacilline-tazobactam), because of the increased anaerobic or aerobic coverage to kill the bacteria.In critically severe patients, a combination of two or more antibiotic is preferred. But there is no difference in overall mortality between monotherapy and combination therapy. The most common causative organism for bacterial sepsis is gram negative organism. In gram negative organism, Echerichia coli,is the most. The time of treatment is very important in the treatment of sepsis. Administration of antibiotics within one hour from admission showed better prognosis when compared with treatment started after one hour, so the time must be taken into consideration for the treatment of sepsis Early goal directed therapy are given inorder to treat hypoxemia, hypotension, hypovolemic conditions of patients. Vasopressors are preferred in certain conditions were IV fluids fails to correct the circulatory dysfunctions.

Published by: Mathew George, Lincy Joseph, Rani Manju, Bhagyalekshmi S

Author: Mathew George

Paper ID: V4I4-1455

Paper Status: published

Published: August 14, 2018

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Research Paper

Comparative study on GFRP and steel tube reinforced GFRP composite in terms of strength to weight ratio

Composite materials with high specific strength and specific modulus properties are mainly used in the automotive and aerospace industries. Currently, a lot of research is happening on advanced composite materials in order to improve these properties. The objective of the present work focused on, the studies related to the effect of laterally reinforced hypodermic steel tubes in Glass Fiber Reinforced Plastic (S-GFRP) composite by estimating strength to weight ratio. These specimens were prepared using hand layup process. From experimental data, mechanical properties like ultimate compressive ultimate strength, stiffness, strength to weight ratio determined. The experimental results show that a GFRP specimen with lateral reinforcement of hypodermic steel tubes (S-GFRP) give high stiffness and high strength to weight ratio compared to that of plane fiber reinforced plastic (GFRP).

Published by: Avinash G Hiremath, Nagraj Biradar, G. G. Giridhara

Author: Avinash G Hiremath

Paper ID: V4I4-1468

Paper Status: published

Published: August 14, 2018

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Research Paper

A prospective study on drug utilisation pattern of cephalosporins in respiratory tract infections

Drug Utilization Pattern is defined by WHO in 1977 as "the marketing, distribution, prescription and the use of drugs in a society, with special emphasis on the resulting medical, social and economic consequences”. The aim is to evaluate the Drug Utilization Pattern of cephalosporins in respiratory tract infections. Methods: In a prospective observational study performed over a 6 months period (2017-2018), hospitalized adult patients who received cephalosporins for respiratory tract infections were selected. The collected data included demographic details, information regarding a cough, phlegm, periods of a cough and phlegm, breathlessness, wheezing, chest illness, past illness, tobacco, and smoking. Over the study period, 185 patients were evaluated. Lower Respiratory Tract infected patients (130) 70.3% were more than Upper Respiratory Tract (55) 29.7%. Majority patients came with a complaint of breathing (113) 61.1% difficulty following by acute exacerbation of COPD (39) 21.1%. First, second and third generation cephalosporins were prescribed. Out of which, the third generation were mostly prescribed than the other two; ceftriaxone 51.4% and cefixime 22.2 %.Around (83) 44.9% patients were having co-morbid conditions, diabetes followed by hypertension.

Published by: Mathew George, Lincy Joseph, Dr. Sujith K, Monisha Mohan

Author: Mathew George

Paper ID: V4I4-1449

Paper Status: published

Published: August 14, 2018

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Research Paper

Effect on properties of concrete using Bricks Kiln Dust (BKD)

Sustainable resources management and development have been at the forefront of an important issue concerning the construction industry for the past several years. Specifically, the use of sustainable building materials and reuse of waste materials is gaining importance and becoming commonplace in many areas. As one of the most commonly used construction materials in the world, concrete composed of natural aggregate, natural sand, cement, and water, out of these raw materials for concrete, cement can be manufactured in industries but natural aggregates are non renewable resources and depleting at an alarming rate, results in scarcity of good quality natural occurring aggregates (coarse and finer one). In the present study the hardened properties like compressive strength, split tensile strength, and also durability properties like ISAT, test were carried out on Brick kiln dust concrete. The percentage of bricks kiln dust that partially and fully replaced by fine aggregates by weights were 0%, 20%, 40%, 60%, 80% and 100%. Experiments were conducted for both Ordinary Concrete and bricks kiln dust Concrete with different percentages of BKD. It is observed from the experimental results and its analysis, that the compressive strength of concrete, splitting tensile strength of concrete increases with the addition of low Percentage of bricks kiln dust. The results show that the optimum replacement of recycled bricks kiln dust with fine aggregates was 20%. Up to 20% replacement, it is possible to gain the same strength as conventional concrete. Beyond 20% replacement the strength results following a decreasing trend.

Published by: Himanshu Pratap Singh, Ram Bharosh

Author: Himanshu Pratap Singh

Paper ID: V4I4-1459

Paper Status: published

Published: August 13, 2018

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