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Review Paper

Body-on-a-chip: Microfluidic based futuristic approach for Drug Screening

Preclinical testing using animal models has been crucial in drug development process, but issues of ethical factors and species variances still remain. However, human derived in vitro cell-based assays are being actively practised to study drug’s pharmacokinetics and pharmacodynamics. Although, current in vitro cell assays give the drug's potential therapeutic benefits, it is only specific to a tissue but not to an entire body to accurately predict the compound’s efficacy, toxicity and inter-organ interactions. In recent years, ever-growing scientific research and innovative advancements in microfabrication technologies have impacted notably on bioengineering and biomedical engineering. One such approach is ‘Microfluidics’ that has emerged as a powerful tool to provide the opportunity to stimulate different organs. The technology of organ-on-a-chip has made it probable to physically and chemically recapitulate the in-vivo conditions by utilising microfluidic approach. Till now, in vitro models of multi-organs including the gut, liver, kidney, lung, heart, and bone have been developed to mimic the organ physiology. Likewise, an integration of multiple organs on a microfluidic platform known as body-on-a-chip model has also been proposed to replicate organ cross talk. This review provides a overview on cell culturing within microfluidics systems, design, fabrication of biochips, organ and body on a chip models, and its applications in the coming future.

Published by: Aishwarya Rajan, Neeta Shivakumar

Author: Aishwarya Rajan

Paper ID: V7I3-1534

Paper Status: published

Published: June 1, 2021

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Research Paper

Condition monitoring of single-stage gear pair using vibration analysis

In this study, an involute gear pair is designed and fabricated. A test rig is assembled to carry out the experiment in which the driving gear is subjected to different crack levels and its vibrational signatures are studied using vibrational analysis. Generation of a two-level severity root crack on the gear model for the simulation segment is done using SOLIDWORKS, and cracks of the same dimensions are replicated on the fabricated gear using a Wire-Cut Electrical Discharge Machine. The vibrational properties of the motor are then recorded under different speeds and loads for both crack severities and are compared to that of a flawless gear of the same properties and dimensions. This further allows us to observe the effect of operational parameters on the vibrational properties of the motor that runs the defective gears. This study reveals the relationship between the waveforms of the vibration and cracks severity of the gears along with parameters such as varying speeds and loads.

Published by: Arko Banerjee, Vaibhav Radhakrishnan, Rajkaran Singh Bhatia

Author: Arko Banerjee

Paper ID: V7I3-1629

Paper Status: published

Published: June 1, 2021

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Research Paper

Effects of addition of Carbon Nanotubes on the properties of concrete

Nowadays, Environmental pollution is one of the greatest problems the world is facing which is causing grave & the damage which is not reparable to the world & about 40% humans have died due to air, water & soil pollution. India is now the 4th country in the world to generate nearly 2,454,938 kilo tonnes is carbon dioxide per year. To reduce the carbon emission we can use a material which is called carbon nanotubes (CNT's ). Carbon nanotubes are the materials which have special properties & great potential in various Civil engineering structure. We can convert the waste gases coming from the industrial & automobile or vehicular exhaust or furnace into nanoparticles called carbon nanotubes which is almost three thousand times stronger than steel & one-sixth of its weight. Carbon nanotubes are currently receiving more interest because is their’s extremely good mechanical properties & are now know to be materials of the 21st century. In the present study the effect of the addition of carbon nanotubes on the properties of concrete to be studied. And the comparison between carbon nanotubes & conventional concrete will carry out.

Published by: Tejas S. Alurkar, Prashant D. Waghmare, Swapnil S. Jagtap, Prabhu H. More, Baliram R. Warvate

Author: Tejas S. Alurkar

Paper ID: V7I3-1352

Paper Status: published

Published: June 1, 2021

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Research Paper

An Inclusive design approach for visually challenged

Fashion designers and brands have been developing garments taking specific consumers, including people with some sort of disability. The main purpose of this project is to analyse the challenges faced by visually challenged young women and develop inclusive design approach to non-discriminate them from experiencing fashion through the research of elements, aspects and concepts that can be useful for this cause. During research, informative papers, articles, studies were found to address inclusive design approach as a useful tool for the development of inclusive products for the physically challenged.

Published by: Niveathita S., Sanjuvikasini G. S., Vinita S.

Author: Niveathita S.

Paper ID: V7I3-1281

Paper Status: published

Published: June 1, 2021

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Research Paper

AR based smart education in android platform using unity

Augmented reality is a rapidly growing subject of computer science and technology study. AR brings technology to life by allowing users to interact with their surroundings in real time. Information and communication technology now supports the growth of human contact with physical, computer, and virtual environments in fields such as science, commerce, banking, and education. This technology is a part of computer science that concerns with the merging of reality and computer-related data. It is common knowledge that our existing educational system falls short in several areas. We still follow the traditional blackboard method of teaching which fails to provide every student with proper guidance. By introducing Augmented reality into the education system, teachers can convey their knowledge more precisely and in a very attractive manner. Some concepts are difficult to understand and even harder to properly depict and present in a textbook. However, augmented reality serves as a new medium where it is much easier to achieve. In this application the topics can be observed in 3D graphical image and video format replacing the traditional 2D view. This system is designed to provide virtual training to the hyperactive person as well to conduct intelligent assessment to the same person. Therefore this deployment can also be done for creating a classroom environment for all the learners, which initiates more interaction to learners via MQTT protocol , and they can see all practical implementation of their subject through a virtual mode, reducing learners' stress in understanding a subject. This system will help the students to view the 2D images in 3D which gives students better visualization and helps it easier to understand various layers, structures which otherwise is difficult to understand based on just a 2D structure.

Published by: Devika Vinod, Aishwarya C., Vinmathi M. S., Dr. Kavitha Subramani

Author: Devika Vinod

Paper ID: V7I3-1599

Paper Status: published

Published: May 31, 2021

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Research Paper

RFID-based health services for remote areas

Nowadays healthcare technology is aiming towards empowering people to live a healthier life with the help of IoT. The health care industry has been adopting and utilizing information and communication technologies (ICT) for efficient health care administration. Recent developments in wireless sensors, communication and information network technologies have created a new era of the Internet of things (IoT)1. The concept of the automated health care system and smart medical devices bears enormous potential for the well-being of people majorly in remote areas. Patients who can not visit the hospitals regularly can be constantly monitored using IoT-driven monitoring. This type of solution includes sensors to collect comprehensive symptoms as well as information and uses gateways and send the analyzed data wirelessly for further analysis and review if needed. It replaces the process of having a health professional come by at regular intervals to check the patient’s vital signs, instead of providing a flow of information at certain intervals. The main aim of our project is to provide an alternative to the current system in rural areas and providing basic level diagnosis as well as prescriptions and ambulance support if needed by the use of technology.

Published by: Rajeshree Vilas Pohokar, Dr. Pradnya Mathurkar, Rani Pawar, Krishna Sandel

Author: Rajeshree Vilas Pohokar

Paper ID: V7I3-1596

Paper Status: published

Published: May 31, 2021

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