Manuscripts

Recent Papers

Research Paper

Study of different blind spot detection techniques

A blind spot in a vehicle is an area around the vehicle that cannot be directly observed by the driver while at the controls. Blind spots exist in a wide range of vehicles: aircraft, cars, motorboats, sailboats, and trucks. Other types of transport have no blind spots at all, such as bicycles, horses, and motorcycles. Blind spots represent an extreme danger for motorists, especially at highway speeds; each year, thousands of accidents happen when drivers change lanes and collide with other vehicles that were in their blind spots. According to the National Highway Traffic Safety Administration, blind spot-related accidents are responsible for more than 800,000 accidents and more than 300 fatalities each year. These accidents are especially difficult to avoid because even practicing defensive driving is not always enough to prevent them; you cannot react to a vehicle that you cannot see. Proper adjustment of mirrors and use of other technical solutions can eliminate or alleviate vehicle blind spots. The goal of this paper is to study different blind spot detection techniques and to have a comparison between them.

Published by: Mashmoom Shaikh, Rohini Pise

Author: Mashmoom Shaikh

Paper ID: V4I6-1265

Paper Status: published

Published: November 27, 2018

Full Details
Research Paper

Development and validation of assay method for estimation of Apixaban in bulk drug and its marketed formulation

The paper involves the development of a simple, precise and sensitive method for estimation of Apixaban in bulk drug and its marketed formulation using a reverse-phase liquid chromatographic method. The separation was achieved on C18 INERTSIL ODS-2 Column (250 mm×4.6 mm×5 um) using mobile phase (Buffer: ACN) in the ratio of 55:45(v/v) with a run time of 15 minutes and wavelength for estimation of Apixaban was taken as 280 nm. Literature survey reveals that there are very few HPLC, UV methods were available Hence an attempt has been made to develop an RP-HPLC method for estimation of Apixaban. The developed method was validated for Linearity, Accuracy (% Recovery), Precision, LOD, and LOQ etc. the linearity was found to be in the range of 1-3 μg/ml with correlation coefficient found for linearity is 0.999. The developed and validated RP-HPLC method is applied for the identification of eluted.

Published by: Anuja Sanjay Chitale, Purnima Hamrapurkar

Author: Anuja Sanjay Chitale

Paper ID: V4I6-1291

Paper Status: published

Published: November 27, 2018

Full Details
Research Paper

Analytical method development and validation for estimation of Dapagliflozin in bulk and pharmaceutical dosage form using RP-HPLC

The incidence of diabetes is growing rapidly both in India and worldwide. Dapagliflozin is a drug of the gliflozin class which is a sodium-glucose cotransporter – inhibitor (SGLT-2), which prevent glucose reabsorption in the kidney. The present investigation is concerned with method development and validation of simple, precise, accurate, reproducible and specific reversed-phase high-performance liquid chromatography (RP-HPLC) method for estimation of Dapagliflozin in bulk and pharmaceutical dosage form using an INERTSIL ODS-2 C18 column (250mm x 4.6mm x 5µ) column in isocratic mode with 0.01 M Ammonium Formate Buffer (pH 3.5): Acetonitrile (50:50 v/v) as mobile phase at a flow rate of 1ml/min. The determination of analyte was carried out at 224nm using a PDA detector. The retention time for Dapagliflozin was found to be 4.7 min. The proposed method has permitted the quantification of Dapagliflozin over linearity in the range of 1.25 – 3.75 µg/ml and its mean recovery were found to be 99.91%. The % RSD of intraday and interday precision were found 0.40% and 0.46%. The proposed method was applied successfully for the determination of Dapagliflozin in a pharmaceutical dosage form.

Published by: Ruchita Rajendra Kanade, Dr. Purnima Hamrapurkar

Author: Ruchita Rajendra Kanade

Paper ID: V4I6-1290

Paper Status: published

Published: November 27, 2018

Full Details
Research Paper

A randomized comparison of effectiveness of modified constraint induced movement therapy versus conventional physiotherapy on upper-extremity dysfunction in the treatment of adult hemiplegia

This study is designed to compare the effectiveness of Modified Constraint-Induced Movement Therapy Versus Conventional Physiotherapy for improving involved upper extremity movement efficiency in Adult Hemiplegic patients. To know the effectiveness of Modified Constraint-Induced Movement Therapy on Upper Extremity dysfunction for management of Adult Hemiplegia. The study is carried out at the Vihar Hospital, Anand. 40 patients of adult hemiplegia were recruited into two groups after inform consent was taken from all patients. Group 1: Experimental group received Modified Constraint-Induced Movement Therapy (mCIMT) which includes active/passive Mobility exercises, Muscle Stretching, Muscle Strengthening, Weight Bearing Exercises, Task-specific and Fine motor practice of affected upper limb. Group 2: control group received conventional physiotherapy which includes active/passive mobility exercises, muscle stretching, muscle strengthening, weight bearing exercises, throwing a ball, moving, transferring, reaching and manipulating an object with detailed evaluation including ARAT score were taken as a baseline as well as postoperatively after the 4th week of treatment. Both the groups showed clinically and statistically significant improvement in total ARAT score at 4-weeks. The total ARAT scores had improved by 38.10 % in the experimental group and by 20.61 % in the control group. Results of the study concluded that there was a significant improvement in both the groups; however the Modified Constraint-Induced Movement Therapy group was more effective for improving involved upper extremity movement efficiency in patients of adult hemiplegia.

Published by: Sapna S. Gupta

Author: Sapna S. Gupta

Paper ID: V4I6-1283

Paper Status: published

Published: November 27, 2018

Full Details
Research Paper

Effects of combined osmotic drying methods on quality characteristics of orange slice

Orange is a food with high content of healthy nutrients and it has great tradition and economic importance in Valencia. The development of new orange products would be a good way to promote the consumption of this fruit, improving the nutritional health of society. In this way, the osmotic dehydration (OD) has been widely used for conservation and design of new products from fruits. Orange slices have been osmotically dehydrated using as osmotic agents healthy sweeteners sucrose. Tray drying of orange slices was conducted in two stages. In the first stage, osmosis was carried out using three different concentrations of sugar solution (40%,50%,60%) with 1.5% potassium metabisulphite (KMS) at 600 c temperature were maintain for 16 hour. The combination of different samples was slightly increased with different storage period. The combined effect of solution temperature, sugar concentration and time of moisture loss was investigated by developing treatment combinations. It was found that relationship exists between moisture loss and solution temperature, sugar concentration and time. The final conditions of osmotic dehydration were determined on the basis of permissible moisture loss in orange slices and were found as 60% sugar solution concentration, 600c solution temperature and 16 hour time. The best process temperature was selected on the basis of statistical analysis of quality parameters, namely, rehydration ratio, dehydration ratio, sugar content, carbohydrate content, protein content fat content, ash content vitamin C content acid and sensory quality parameters(color ,texture taste, appearance, overall acceptability) and it was 600 C tray drying temperature requiring 16 hour drying time.

Published by: Sneha Shukla, Mayank Tripathi, Avinash Kumar

Author: Sneha Shukla

Paper ID: V4I6-1289

Paper Status: published

Published: November 27, 2018

Full Details
Research Paper

Effect of waviness in the bearing on the life of rotating element

Rotating structures or more general structures with constant but otherwise arbitrary velocity are important elements of machinery as rotor shafts and blades of the propellers, helicopters or the wind turbines. Vibrations in such structures require special attention. The vibrations may cause a reduction in the life cycle of the rotating elements. But it must be noted that some vibration frequencies can be acceptable for the rotating element to sustain its life cycle. Sometimes, the vibrations may not have any impact on the life of the rotating element. That is the reason this study is undertaken. This project intends to study the impact of vibrations on the life cycle of the rotating elements when the vibrations are due to waviness in the bearing. One of the main objectives of the project is to study the frequency at which the elements can be rotated with waviness in the bearing without affecting the life cycle of the elements. In this project, the 3D model of the bearing and rotating elements is modeled in modeling software and analyzed in ANSYS. Then the vibration frequencies for which the rotating element will sustain its life is analyzed using Vibration and Fatigue analysis in ANSYS. Then for that frequency, an experimental analysis is conducted for evaluating the rpm of the rotating elements.

Published by: Pratibha Kale, Santosh R. Wankhade

Author: Pratibha Kale

Paper ID: V4I6-1259

Paper Status: published

Published: November 27, 2018

Full Details
Request a Call
If someone in your research area is available then we will connect you both or our counsellor will get in touch with you.

    [honeypot honeypot-378]

    X
    Journal's Support Form
    For any query, please fill up the short form below. Try to explain your query in detail so that our counsellor can guide you. All fields are mandatory.

      X
       Enquiry Form
      Contact Board Member

        Member Name

        [honeypot honeypot-527]

        X
        Contact Editorial Board

          X

            [honeypot honeypot-310]

            X