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Comparative evaluation of quantification of gastroretentive drugs through ultraviolet spectrophotometer and high-performance liquid chromatography

Quantification is a major step in the pharmaceutical industry for determining the quantity and quality of a specific Active Pharmaceutical Ingredient in each drug formulation. This step is a major step for commercializing and marketing the drug. Several methods have been developed for the quantification of the drug but the most used are UV and HPLC methods. In this study, we try to review the various quantification methods by UV and HPLC and accomplish that which method is better for the Quantification of Gastroretentive drugs. Gastroretentive drug delivery system is a type of drug which retains for a prolonged time in the Gastrointestinal tract and does not get disintegrated immediately. One type of Gastroretentive drug is Gastroresistant drugs which do not disintegrate regardless of the acidic pH of the stomach but gets absorbed in the surface of the intestines at a basic pH. This is possible because these types of drugs are enteric-coated. Spectrophotometry techniques can be used as an alternative method for HPLC for the quantification of Gastroretentive drugs.

Published by: Santripta Bhowmik

Author: Santripta Bhowmik

Paper ID: V7I2-1399

Paper Status: published

Published: April 17, 2021

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Research Paper

ECG simulator

An electrocardiogram is information of heart signals and activities of an individual measured by electrocardiography using an electrocardiograph machine. Machines tend to have malfunctions, failures, errors, damages, and misuse on usage. Medical equipment cannot be neglected to exist with such factors as it is concerned and connected to the lives of patients. There are several medical errors repetitively ruining several lives every year globally. Therefore, in this case, an ECG Simulator is used to perform calibration and testing over the instruments such as patient monitors and other electrical heart activity recording equipment periodically. To make this viable to every region, we need an economically convincing model. Models: We developed a simulator with basic electronic components for normal sinus rhythm signals generating over 60 and 120 beats per minute. We also developed another simulator that can be loaded with processed ECG arrhythmia signals essential to effectively test any instrument. Result: Both the models produced a promising output as per their configuration respectively.

Published by: Arjoon R. S.

Author: Arjoon R. S.

Paper ID: V7I2-1400

Paper Status: published

Published: April 16, 2021

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Research Paper

Lost in the dark, a unity engine based videogame

In this paper, we present the design and implementation of a game called Lost In The Dark. It is a unique game and developed keeping Windows Operating Systems in mind. The purpose of this project was to promote small-scale video games. The students playing our game go through FPP (First Person Perspective) in a dark place to find their way out where he simultaneously survives from the unknown entities. The player can elevate and complete the tasks so that he can move up to the next level in this unity-powered game.

Published by: Anudeep Vadrevu, Manpreet Dhindsa, Hari Krishna Bommisetty, Bharadwaj Goud Relangi, Sai Krishna Penugonda, Venkata Naga Sai Harshit Manikonda

Author: Anudeep Vadrevu

Paper ID: V7I2-1395

Paper Status: published

Published: April 16, 2021

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Research Paper

Comparative analysis of hexahedral and tetrahedral mesh of guide bracket

In the following paper, an effort has been made to do the comparative analysis of hex mesh and tetrahedral mesh of a guide bracket to decide which mesh type to prefer in order to get accurate results in considerably less time. To analyze whether there is a significant impact of using hex dominant mesh and tetrahedral mesh. The bracket used in the analysis is modeled using solid works 2018 and the finite element analysis is done using “ANSYS 2020 R2 student workbench”. From the finite element analysis, I witnessed that there was a significant difference in the processing time of the two types of mesh and other parameters such as stress and strain were also having a noticeable increase with respect to results in the tetrahedral mesh. The results will thus help to gain knowledge on which mesh is best for future meshing on various models.

Published by: Ashay Katrojwar

Author: Ashay Katrojwar

Paper ID: V7I2-1376

Paper Status: published

Published: April 16, 2021

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Review Paper

Literature survey on the elimination of effect on power transformers by using differential protection

The word “Elimination” is generally used to describe the whole concept of removing or controlling the error value to the stationary value of the power system. In this paper, an effort is made in the direction of development in the protection of power transformers. Protection of all types of transformer in the power system is very important for normal operation of the power system. Among the various operation of power transformer differential operation is a very common method. In this paper, we review the concept of power transformer differential protection then analyze the problem of transformer differential protection to find the solution. We then analyzed the different types of fault for study.

Published by: Kaustubh R. Sonar, Chetan M. Bobade

Author: Kaustubh R. Sonar

Paper ID: V7I2-1381

Paper Status: published

Published: April 15, 2021

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Research Paper

Static structural analysis of a water sprinkler using Ansys workbench

This paper contains a brief analysis of a mechanical component, which is used in almost all sorts of construction businesses, viz. “water sprinkler” in Fire Sprinkler System. The paper highlights changes observed in the results of the component, after analyzed with different meshing viz. linear-ordered tetrahedron; Quadratic-order tetrahedron; and Auto meshing provided by ANSYS workbench. The concentration graph is provided for visual analysis of critical portions (suggested to refer to the values instead). The result specifies the most appropriate meshing in order to obtain precise static structural analysis in efficient time.

Published by: Shravan Sanjay Pardeshi

Author: Shravan Sanjay Pardeshi

Paper ID: V7I2-1379

Paper Status: published

Published: April 15, 2021

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