Premenstrual syndrome (PMS) is a common cyclical condition among women of reproductive age, characterized by physical, psychological, and behavioural symptoms during the luteal phase of the menstrual cycle. The study aimed to assess the knowledge, attitude, and coping strategies regarding PMS among female undergraduate students. A quantitative approach with a descriptive research design was adopted, and 150 female undergraduate students were selected using convenience sampling from a selected college in Kollam district. The findings revealed that 48.7% (n=73) had average knowledge, 97.3% (n=146) had a positive attitude, and 50% (n=75) adopted moderate coping strategies. There was significant Association between the knowledge regarding premenstrual syndrome and selected Demographic variables and no significant association was found between attitude towards PMS and selected demographic variables. The study concluded that the majority of students had average knowledge, a positive attitude, and moderate coping strategies regarding PMS.