Neuroscientific practice is constantly evolving, improving, and developing. Recent research has introduced novel methods to treat pressing conditions which have affected the human population for many decades. This paper delves into the potential of a stimulation technique- deep brain stimulation- to treat the symptoms of a mood disorder as complex and convoluted as depression. Overall, 5 domains were considered, including: an overview of the diagnostic factors of depression, the biological causative factors for depression, current treatment opportunities, the mechanism of DBS and its application to treating depression, and finally, the ethical and social implications of implementing DBS as a mainstream form of treatment for cases of extreme depression. Before its utilisation in mainstream practice, the ethical implications, as well as clinical trials assessing the true long-term impacts of such treatment, must be evaluated. How far should the brain be manipulated in order to treat depression, and how could this impact autonomy and patient safety? Across the literature reviewed, DBS serves as a viable and credible means for relieving symptoms of depression and poses a great potential to improve the lifestyle of treated patients, which is ultimately the desired outcome of a neuroscientific endeavour such as this one.