This paper is published in Volume-3, Issue-1, 2017
Area
Chemistry
Author
Anjali Singh, Ayodhya Singh, Vandana Dwivedi
Org/Univ
M.M.H. College, Ghaziabad, India
Pub. Date
21 February, 2017
Paper ID
V3I1-1366
Publisher
Keywords
Eclipta alba, DPPH, BHT, Hydroxyl Radical, Superoxide Radical.

Citationsacebook

IEEE
Anjali Singh, Ayodhya Singh, Vandana Dwivedi. In Vitro Antioxidant Potential of Pure Fractions of Eclipta Alba, International Journal of Advance Research, Ideas and Innovations in Technology, www.IJARIIT.com.

APA
Anjali Singh, Ayodhya Singh, Vandana Dwivedi (2017). In Vitro Antioxidant Potential of Pure Fractions of Eclipta Alba. International Journal of Advance Research, Ideas and Innovations in Technology, 3(1) www.IJARIIT.com.

MLA
Anjali Singh, Ayodhya Singh, Vandana Dwivedi. "In Vitro Antioxidant Potential of Pure Fractions of Eclipta Alba." International Journal of Advance Research, Ideas and Innovations in Technology 3.1 (2017). www.IJARIIT.com.

Abstract

Abstract–Oxidative stress and Ultraviolet (UV) irradiation-induced skin damage, is involved in numerous diseases. Eclipta alba which belongs to Asteraceae family is used traditionally in ayurvedic system of medicine in India for the treatment of liver diseases. Our study shows that water extract of E. alba has a potent effect in scavenging 1, 1-diphenyl-2-picrylhydrazyl (DPPH), chelating ferrous ion, and superoxide radicals, exhibiting IC50 values of 0.21 mg/mL, 1.20 mg/mL, and .49 mg/mL, respectively. Identification and quantification of the wedelolactone, one of the active constituents of the Eclipta alba plant extract, was carried out by HPLC analysis. The result of the present study indicates that the Eclipta alba extract shows a high amount of ascorbic acid, tannins, flavonoids, phenolics, contents. The hydroalcoholic extract of Eclipta alba effectively scavenged free radicals at all different concentrations and showed potent antioxidant potency. Eclipta alba extract shows antioxidative properties.