This paper is published in Volume-7, Issue-3, 2021
Area
Pharmacy
Author
Saroja S. Naubade, Kailash V. Vilegave, Suryakant Hanmantrao Gond, Pratibha M. Chandankar
Org/Univ
Dr. D. Y. Patil Institute of Pharmaceutical Sciences and Research, Pune, Maharashtra, India
Pub. Date
26 May, 2021
Paper ID
V7I3-1460
Publisher
Keywords
Bisoprolol Fumarate, Fast Dissolving Tablet, Crospovidone, Croscarmellose Sodium

Citationsacebook

IEEE
Saroja S. Naubade, Kailash V. Vilegave, Suryakant Hanmantrao Gond, Pratibha M. Chandankar. Overview of fast dissolving tablets of Bisoprolol Fumarate and its patented products, International Journal of Advance Research, Ideas and Innovations in Technology, www.IJARIIT.com.

APA
Saroja S. Naubade, Kailash V. Vilegave, Suryakant Hanmantrao Gond, Pratibha M. Chandankar (2021). Overview of fast dissolving tablets of Bisoprolol Fumarate and its patented products. International Journal of Advance Research, Ideas and Innovations in Technology, 7(3) www.IJARIIT.com.

MLA
Saroja S. Naubade, Kailash V. Vilegave, Suryakant Hanmantrao Gond, Pratibha M. Chandankar. "Overview of fast dissolving tablets of Bisoprolol Fumarate and its patented products." International Journal of Advance Research, Ideas and Innovations in Technology 7.3 (2021). www.IJARIIT.com.

Abstract

Recently, fast-dissolving drug delivery systems have started gaining popularity and acceptance as one such example with increased consumer choice, for the reason of rapid disintegration or dissolution, self-administration even without water or chewing. Various formulations were prepared by direct compression method using different concentrations of crospovidone (2-8%) and croscarmellose sodium (2-8%) as super disintegrants. Formulations were evaluated for precompression parameters and post compressional parameters like uniformity of weight, thickness, hardness, friability, drug content, wetting time, the water absorption ratio, in vitro disintegration time, and in vitro dissolution study. These kinds of dosage forms are also convenient for children, elderly patients with swallowing difficulties, and in the absence of potable liquids. Zydis products are packed in blister packs to protect the formulation from moisture in the environment. Nano-crystal technology avoids manufacturing processes such as granulation, blending, and tableting, which is more advantageous for highly potent and hazardous drugs. Flash Tab Technology involves the preparation of a rapidly disintegrating tablet, which consists of an active ingredient in the form of microcrystals. Oraquick utilizes taste-masking microspheres technology called a micro mask, which provides superior mouth feel, significant mechanical strength, and quick disintegration/dissolution of product. Flash Dose Technology consists of a self-binding shear form matrix termed as "floss". Shearform matrices are prepared by flash heat processing.