Medicinal plants contain numerous biologically active compounds which are helpful in improving the life and treatment of diseases and these are the primary source of synthetic and traditional herbal medicine. The presence of various life-sustaining constituents in plants made scientists investigate these plants for their uses. The objective of the work was to formulate a mosquito repellent product containing Curcumin and Embelin obtained from Curcuma longa and Embelia ribes respectively. Isolated Curcumin and Embelin were confirmed by TLC technique. Bands were compared with standards by calculating Rf 0.74 and 0.60 respectively at visual detection and 254 nm. The formulation of cream was evaluated for various parameters like smooth texture and spreadability with a pH 7 which is non-irritant and suitable for the skin. There is no phase separation during thermal stability. From the present work, it was concluded that 1% Curcumin and 1.5% Embelin containing cream is safe, effective, usable for the skin and stable too.