In 2022, the Tanzanian government made strides in Artificial Intelligence (AI) by establishing an AI laboratory in the capital city of Dodoma, focusing on healthcare, agriculture, and other initiatives. In recent years, the integration of AI technology in information systems has increasingly influenced organizational communication practices, with higher learning institutions experiencing a remarkable adoption of AI in learning. This study aimed to investigate the contribution of AI in organizational communication at Muhimbili University of Health and Allied Sciences (MUHAS), with a particular focus on its current applications, impact on communication roles, and ethical implications. The study employed a descriptive quantitative design involving surveys distributed to students and staff to assess AI usage, effectiveness, and ethical concerns. Data were analyzed through descriptive statistics and regression analysis. Findings show that 78% of respondents acknowledged AI technologies, such as chatbots and virtual meeting platforms, significantly improving organizational communication efficiency and accessibility. However, 45% raised concerns about data privacy and transparency with the use of AI. At the same time, AI-enhanced communication at MUHAS, data security and ethical challenges require attention. The study recommends expanding AI usage, improving data security, and providing training on the ethical application of AI in communication.