This paper is published in Volume-6, Issue-1, 2020
Area
Pharmaceutical Chemistry
Author
Shilpa S. Kurup
Co-authors
Lincy Mathew, Santhosh M. Mathews
Org/Univ
Pushpagiri College of Pharmacy, Thiruvalla, Kerala, India
Pub. Date
21 February, 2020
Paper ID
V6I1-1265
Publisher
Keywords
Glycosylation, Thiourea, Phenol, Aromatic aldehyde, Antibacterial activity

Citationsacebook

IEEE
Shilpa S. Kurup, Lincy Mathew, Santhosh M. Mathews. Synthesis, characterization and screening of novel glycoside derivatives of thiourea for antimicrobial activity, International Journal of Advance Research, Ideas and Innovations in Technology, www.IJARIIT.com.

APA
Shilpa S. Kurup, Lincy Mathew, Santhosh M. Mathews (2020). Synthesis, characterization and screening of novel glycoside derivatives of thiourea for antimicrobial activity. International Journal of Advance Research, Ideas and Innovations in Technology, 6(1) www.IJARIIT.com.

MLA
Shilpa S. Kurup, Lincy Mathew, Santhosh M. Mathews. "Synthesis, characterization and screening of novel glycoside derivatives of thiourea for antimicrobial activity." International Journal of Advance Research, Ideas and Innovations in Technology 6.1 (2020). www.IJARIIT.com.

Abstract

This research highlights the synthesis of glycoconjugates and recent progress in the development of glycosylated derivative therapeutics. This study lies in the discussion of recent mechanistic theories and supporting experimental evidence on chemical glycosylation on compounds. Here synthesized 10 novel glycosylated derivatives of Thiourea. Glycosylation reaction is achieved by using D-glucose and D-fructose. They were characterized by elemental analysis, IR, and 1HNMR spectroscopies. All the synthesized derivatives were screened for in-vitro antibacterial activity against Bacillus subtilis, Staphylococcus aureus, Escheria coli, and Pseudomonas aeruginosa.
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