This paper is published in Volume-6, Issue-2, 2020
Area
Synthesis and Molecular Docking Study
Author
Awinash Chavan
Co-authors
Prafulla Sabale
Org/Univ
Raosaheb Patil Danve College of Pharmacy, Badnapur, Maharashtra, India
Pub. Date
18 March, 2020
Paper ID
V6I2-1258
Publisher
Keywords
Synthetic Flavone, Claisen-Schmidt Condensation Reaction, Anti-inflammatory, Celecoxib

Citationsacebook

IEEE
Awinash Chavan, Prafulla Sabale. Synthesis and anti-inflammatory activity of some 2-(3’-aminesubstituted)-7- hydroxyl-4H-1-benzopyran-4-one derivatives, International Journal of Advance Research, Ideas and Innovations in Technology, www.IJARIIT.com.

APA
Awinash Chavan, Prafulla Sabale (2020). Synthesis and anti-inflammatory activity of some 2-(3’-aminesubstituted)-7- hydroxyl-4H-1-benzopyran-4-one derivatives. International Journal of Advance Research, Ideas and Innovations in Technology, 6(2) www.IJARIIT.com.

MLA
Awinash Chavan, Prafulla Sabale. "Synthesis and anti-inflammatory activity of some 2-(3’-aminesubstituted)-7- hydroxyl-4H-1-benzopyran-4-one derivatives." International Journal of Advance Research, Ideas and Innovations in Technology 6.2 (2020). www.IJARIIT.com.

Abstract

A series of 2-(3’-aminesubstituted)-7- hydroxyl-4H-1-benzopyran-4-one amine derivatives has been synthesized by condensation of 2,4-Dihydroxyacetophene (1.40 ml) and 3-Chlorobenzaldehyde (0.01 mole) through Claisen-Schmidt condensation reaction. Novel flavone derivatives were access for anti-inflammatory activity by using carrageenan induced rat paw edema method. Among the synthesized compounds (t, v, w, k) shows good anti-inflammatory activity comparable to reference drug (Celecoxib).
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