Pyrazolines are well-known and important nitrogen-containing 5-membered heterocyclic compounds. Pyrazolines are known to exhibit different biological and pharmacological properties such as anticancer, antibacterial, antifungal, and ant tubercular activities. Chalcones with an enone group between two aromatic rings exhibit remarkable pharmacological activities such as anti-inflammatory, antibacterial, antitumor, antifungal activity.