Pelvic inflammatory disease (PID) is the commonest disease of the reproductive-aged, sexually active women, that leads to serious complications if left untreated. It is a polymicrobial infection caused by chlamydia, trichomonas but can occur from other sources of bacteria. PID is diagnosed in more than one million women each year in the United States. In classical Unani texts, Waram-Al-Rahim manifests specific as well as associated symptoms due to anatomical proximity of the uterus, and other causes like derangement in Akhlat, asbab-i-badiya o sabiqa etc causing the Rahim to easily affected & disturbed Af’al-i- Tabiyya which if it is not treated adequately, it becomes warm al rahim sulab which is difficult to treat. Various compound formulations are mentioned in Unani classical text for Waram-Al-Rahim possessing the properties of Musaffi-E-Khoon, muhallil warm, dafia’h ta’ffun, dafia’h huma, muqawiyat, Qabizat, Radi, etc. This review article gives a detailed description of waram al-rahim including its causes, pathogenesis, sign and symptoms, and principle of treatment in the Unani system of medicine.