Bilayer tablets can be used to control the delivery rate of one or two different active pharmaceutical ingredients. Presently the use of bilayer tablets has been increased. Bilayer tablets can be a primary option to avoid chemical incompatibilities. The main goal of the present analysis work was to prepare bilayer tablet of Metoclopramide hydrochloride and Aceclofenac for separate layers to avoid the loss of dignity of the drug. Bilayer tablet manufacturing is addressed including material properties, lubrication, layer ordering, layer thickness, layer weight control, as well as first and final compression forces. These days, several pharmaceutical organizations are developing bilayer tablet for co-administration of drugs to improve the therapeutic efficacy as well as to reduce the chances of drug-drug interaction.