Transcription is the mechanism through which proteins are formed and it is done at the promoter regions. The structural property and the stability of DNA (Deoxyribonucleic Acid) are due to the promoters and these promoters are used to distinguish them from other genomic sequences. Genomic expression patterns were determined in the yeast S.cerevisiae in response to the environmental fluctuations. To measure these changes, DNA Microarrays were used. It is revealed that the yeast genome contains a TATA box. Those genes associated with the TATA box show response mainly to stress conditions.